abstract：BACKGROUND:Although panic disorder (PD) is suggestive of autonomic nervous system dysfunction, especially in the cardiovascular autonomic system (CAS), the results in many previous studies are still controversial. Using a new physiological index which could well reflect emotional reaction to visual stimuli (Yoshizawa, ...

journal_title：Journal of affective disorders

authors： Shioiri T,Kojima M,Hosoki T,Kitamura H,Tanaka A,Bando T,Someya T

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Most investigations of residual symptoms have focused on partial responders to antidepressant medications. Comparatively few have examined residual symptoms among patients who achieved a more successful response to treatment. In addition, few studies have assessed residual symptoms among patients treated wit...

journal_title：Journal of affective disorders

authors： Ogrodniczuk JS,Piper WE,Joyce AS

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Research examining the association between childhood abuse and depressive disorders has frequently assessed abuse categorically, thus not permitting discernment of the cumulative impact of multiple types of abuse. As previous research has documented that adverse childhood experiences (ACEs) are highly interr...

journal_title：Journal of affective disorders

authors： Chapman DP,Whitfield CL,Felitti VJ,Dube SR,Edwards VJ,Anda RF

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:Rates of relapse and predictive relapse factors were studied over more than 4 years in a sample of Spanish outpatients with DSM-III-R criteria for unipolar major depressive episode. METHODS:A final sample of 139 outpatient was followed monthly in a naturalistic study. The Structured Clinical Interview for D...

journal_title：Journal of affective disorders

authors： Pintor L,Torres X,Navarro V,Matrai S,Gastó C

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:Little is known about the extent to which manic symptoms might influence the self-report ratings of adolescents as compared to parent and teacher ratings, although there are clinical reasons to believe that mania would increase disagreement. METHODS:Parents and youths between the ages of 11 and 17 years wer...

journal_title：Journal of affective disorders

authors： Youngstrom EA,Findling RL,Calabrese JR

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Many neuroimaging studies of patients with bipolar disorder have demonstrated functional hypofrontality (reduced activation of the frontal cortex), although this finding is still controversial. We previously found hypoactivation of the left prefrontal region in remitted subjects with bipolar disorder measure...

journal_title：Journal of affective disorders

authors： Matsuo K,Watanabe A,Onodera Y,Kato N,Kato T

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Pediatric bipolar disorder (BPD) can be misdiagnosed as a depressive, attention, conduct, or anxiety disorder and treatment with antidepressants and stimulants is common. Risk of adverse outcomes related to such treatment remains poorly defined. METHODS:We analyzed clinical records of 82 children (mean age ...

journal_title：Journal of affective disorders

authors： Faedda GL,Baldessarini RJ,Glovinsky IP,Austin NB

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The validity of a sub-classification of affective psychosis according to the mood congruence of psychotic features has been questioned in the literature. While some authors have found a correlation between such symptoms and outcome, their predictive value was rather limited in these studies. METHOD:Prospect...

journal_title：Journal of affective disorders

authors： Conus P,Abdel-Baki A,Harrigan S,Lambert M,McGorry PD

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Psychotic major depression (PMD) and delusional misidentification syndromes (DMS) exhibit cognitive deficits. Since the P300 component of event-related potentials (ERPs) provides valuable information concerning cognition, we studied this component of ERPs in DMS and PMD patients. METHODS:Nine patients with ...

journal_title：Journal of affective disorders

authors： Papageorgiou CC,Alevizos B,Ventouras E,Kontopantelis E,Uzunoglu N,Christodoulou G

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to obtain comprehensive information on steroid metabolism in depressed patients. METHODS:24-h urinary steroids were measured by gas chromatography in patients with unipolar recurrent major depression (URMD) compared to controls, and an index of relative activity of the 11bet...

journal_title：Journal of affective disorders

authors： Poór V,Juricskay S,Gáti A,Osváth P,Tényi T

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Depression treatment by General Practitioners (GPs) and patient outcomes improved significantly after a comprehensive 20-h training program of GPs. This study examines whether the effects on patient outcomes are caused by the improvements in the process of care. METHODS:Seventeen GPs participated in the tra...

journal_title：Journal of affective disorders

authors： van Os TW,van den Brink RH,Tiemens BG,Jenner JA,van der Meer K,Ormel J

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To assess the psychometric properties and the usefulness of the General Behavior Inventory (GBI) in the adolescent age range. METHOD:The GBI, the Schedule for Affective Disorders and Schizophrenia for School Age Children, Kiddie-SADS-Present and Lifetime Version (K-SADS-PL) and the Youth Self-Report (YSR) we...

journal_title：Journal of affective disorders

authors： Reichart CG,van der Ende J,Wals M,Hillegers MH,Ormel J,Nolen WA,Verhulst FC

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was to analyze the impact of pretreatment characteristics and personality disorders on the onset of response in the treatment of panic disorder. METHODS:The data of 73 out-patients with panic disorder who had completed at least 6 weeks of a randomized trial of 24 weeks of either paroxe...

journal_title：Journal of affective disorders

authors： Berger P,Sachs G,Amering M,Holzinger A,Bankier B,Katschnig H

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:There exists a need to identify safe and effective treatments for depression in patients with coronary heart disease (CHD). METHODS:Using a cross-sectional design, 17 depressed patients being treated with bupropion (200-450 mg/day) were compared with 17 depressed patients being treated with paroxetine (10-5...

journal_title：Journal of affective disorders

authors： Straneva-Meuse PA,Light KC,Allen MT,Golding M,Girdler SS

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:In most settings, generalized anxiety disorder (GAD) is highly comorbid with major depressive disorder (MDD). This raises uncertainty about the clinical relevance of GAD as a distinct diagnostic entity. The demonstration of functional impairment attached to GAD, independent of that attributable to MDD, would...

journal_title：Journal of affective disorders

authors： Stein MB,Heimberg RG

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:In 1992, the ICD-10 introduced the concept of mixed anxiety-depression disorder (MAD). However, a study examining the stability of this ICD-10-diagnosis is lacking. Our objective was to examine the 12 month outcome of MAD in comparison to the outcome of depression, anxiety, and comorbid depression and anxiet...

journal_title：Journal of affective disorders

authors： Barkow K,Heun R,Wittchen HU,Bedirhan Ustün T,Gänsicke M,Maier W

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Anger attacks, characterized by sudden episodes of intense anger with autonomic arousal, have been described in patients with major depressive disorder (MDD). This study compared the prevalence and clinical significance of anger attacks in unipolar versus bipolar depression. METHODS:Using the questionnaire ...

journal_title：Journal of affective disorders

authors： Perlis RH,Smoller JW,Fava M,Rosenbaum JF,Nierenberg AA,Sachs GS

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Women who have suffered from one episode of postpartum-onset major depression (PPMD) experience increased risk for recurrence in the year following another birth. METHODS:Non-depressed women (N=51) who had at least one past episode of PPMD were recruited during pregnancy. After birth, subjects were assessed...

journal_title：Journal of affective disorders

authors： Wisner KL,Perel JM,Peindl KS,Hanusa BH

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:The aim of the present trial was to investigate the efficacy and safety of kava special extract WS 1490 in patients with sleep disturbances associated with anxiety, tension and restlessness states of non-psychotic origin. METHODS:In a multicenter, randomized, double-blind clinical study, 61 patients receive...

journal_title：Journal of affective disorders

authors： Lehrl S

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:The burden of comorbid dysthymia and other comorbid psychiatric illnesses in a Canadian primary care setting was measured. Two groups of primary care patients: those who scored positive for comorbid dysthymia versus those who scored negative for any psychiatric disorder were compared. METHODS:This was a cro...

journal_title：Journal of affective disorders

authors： Bell B,Chalklin L,Mills M,Browne G,Steiner M,Roberts J,Gafni A,Byrne C,Wallik D,Kraemer J,Webb M,Jamieson E,Whittaker S,Dunn E

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Several studies from different epidemiological backgrounds have shown that unipolar depression is more prevalent in females than in males. This study examines gender differences in depression in a sample of 4075 probands recruited representatively from the general population in the northern German epidemiolo...

journal_title：Journal of affective disorders

authors： Lucht M,Schaub RT,Meyer C,Hapke U,Rumpf HJ,Bartels T,von Houwald J,Barnow S,Freyberger HJ,Dilling H,John U

更新日期：2003-12-01 00:00:00

abstract：:Predicting response to antidepressant medication has been a challenge to clinicians and researchers for decades. Attention has been paid to the role of motor retardation as a putative indicator of treatment response, yet previous findings have been mixed. One reason for this inconsistency may be related to the subject...

journal_title：Journal of affective disorders

authors： Caligiuri MP,Gentili V,Eberson S,Kelsoe J,Rapaport M,Gillin JC

更新日期：2003-11-01 00:00:00

abstract：:Prior to 1970, childhood depression was not considered a valid clinical entity by American psychiatrists. One of the early clues was provided in the 1950s by the author's observation of depressive symptoms in children and young adolescents with undescended testicles. This finding was extended to children with several ...

journal_title：Journal of affective disorders

authors： Cytryn L

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:The daily pattern of motor activity and the autonomic cardiovascular regulation were studied in major depression to quantify changes in psychomotor function and autonomic cardiac functioning. Additionally, relationships between motor activity parameters, cardiovascular measures and specific clinical features...

journal_title：Journal of affective disorders

authors： Volkers AC,Tulen JH,van den Broek WW,Bruijn JA,Passchier J,Pepplinkhuizen L

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the prevalence and comorbidity of affective disorders, especially current major depressive episode and bipolar disorder among suicide attempters in Hungary. METHODS:Using a structured interview (Mini International Neuropsychiatric Interview) determining 16 Axis I...

journal_title：Journal of affective disorders

authors： Balázs J,Lecrubier Y,Csiszér N,Koszták J,Bitter I

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:The contribution that recently identified risk factors for Postnatal Depression (PND) made to an existing prenatal screening tool ('Predictive Index' of PND; Cooper et al., 1996) was assessed in an attempt to improve the performance of this measure. METHOD:The Predictive Index and measures of appraisal and ...

journal_title：Journal of affective disorders

authors： Honey KL,Bennett P,Morgan M

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Social anxiety disorder is fairly prevalent among alcohol abusing/dependent subjects. The objective of the present study was to investigate: (a) the incidence of social anxiety symptoms in inpatient alcoholics, (b) the effect of alcohol detoxification on these symptoms, and (c) whether a combined psychothera...

journal_title：Journal of affective disorders

authors： Liappas J,Paparrigopoulos T,Tzavellas E,Christodoulou G

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:It is postulated that depressed patients who engaged in self-focused rumination on their depressive symptoms may experience more hopelessness, more interpersonal distress and poorer social functioning while patients who distract themselves may experience less severe hopelessness and better social functioning...

journal_title：Journal of affective disorders

authors： Lam D,Schuck N,Smith N,Farmer A,Checkley S

更新日期：2003-08-01 00:00:00

abstract：:This paper reviews evidence from both human and non-human primate studies concerning the role of early adverse experiences in the onset and course of adult depressive disorders. Despite accumulating evidence that stressful life events can play a major role in precipitating the onset of depressive episodes in humans, t...

journal_title：Journal of affective disorders

authors： Gilmer WS,McKinney WT

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The maternity blues have been studied world-wide and are generally regarded as a cross-cultural phenomenon. However, low prevalence rates of the blues have been reported recently in studies of Japanese women. The purposes of this study are, firstly, to establish whether the low prevalence noted in Japanese w...

journal_title：Journal of affective disorders

authors： Hau FW,Levy VA

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Abnormal social behaviour, which is a common feature of psychiatric disorders, is associated with rejection. A passive lack of participation or involvement has been studied as characteristic of depression but active forms of nonparticipation have received little experimental attention. This study examined th...

journal_title：Journal of affective disorders

authors： Tse WS,Bond AJ

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Impulsivity (I) and anxiety (A) were hypothesized to be crucial clinical features in adolescents with at-risk behavior. We therefore classified them into sub-groups according to these two major dimensions. The study examined the relevance of these groups by describing their major diagnoses and behavioral cha...

journal_title：Journal of affective disorders

authors： Askénazy FL,Sorci K,Benoit M,Lestideau K,Myquel M,Lecrubier Y

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:We assessed the prevalence of mood disturbance among women with prospectively documented polycystic ovary syndrome (PCOS). METHODS:Thirty-two women with PCOS completed the Center for Epidemiological Studies-Depression Rating Scale (CES-D). Clinical and biochemical characteristics were assessed. RESULTS:Six...

journal_title：Journal of affective disorders

authors： Rasgon NL,Rao RC,Hwang S,Altshuler LL,Elman S,Zuckerbrow-Miller J,Korenman SG

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:We tested if duration and intensity of episodes in treatment-resistant affectively ill patients were related to cerebrospinal fluid (CSF) concentrations of monoamine metabolites. METHOD:In retrospective life charts were recorded every previous episode of 37 patients with severe treatment-refractory affectiv...

journal_title：Journal of affective disorders

authors： Ehnvall A,Sjögren M,Zachrisson OC,Agren H

更新日期：2003-04-01 00:00:00

abstract：:The lifetime prevalence of mood disorders in women is approximately twice that of men. The underlying causality of this gender difference is not yet understood. There is increasing scientific attention to the modulation of the neuroendocrine system by fluctuating gonadal hormones. This review attempts to summarize our...

journal_title：Journal of affective disorders

authors： Steiner M,Dunn E,Born L

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Lithium has been found to be effective in reducing suicide rates during long term treatment of patients with bipolar disorders. Data on the efficacy of anticonvulsant mood stabilizers in reducing suicide risk are sparse. METHOD:Charts of 140 bipolar patients treated continuously for a minimum of 6 months du...

journal_title：Journal of affective disorders

authors： Yerevanian BI,Koek RJ,Mintz J

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Recognition by the DSM-IV of rapid cyclicity as a course specifier has raised the question of the stability and long-term outcome of rapid-cycling (RC) patients. Data on this topic is sparse and often inconsistent. To our knowledge, these are the first personally followed patients over the long term, dealing...

journal_title：Journal of affective disorders

authors： Koukopoulos A,Sani G,Koukopoulos AE,Minnai GP,Girardi P,Pani L,Albert MJ,Reginaldi D

更新日期：2003-01-01 00:00:00

abstract：:Despite advances in the pharmacologic treatment of bipolar disorder, it is clear that additional strategies are needed to provide patients with longer-term mood stability. Recent years have witnessed the development of a number of psychosocial strategies for bipolar disorder that are design as adjuncts to ongoing phar...

journal_title：Journal of affective disorders

authors： Otto MW,Reilly-Harrington N,Sachs GS

更新日期：2003-01-01 00:00:00

abstract：:Oxcarbazepine, although structurally similar to carbamazepine, is metabolised very differently. As a consequence, oxcarbazepine's pharmacokinetic profile is comparatively less complex, and a more predictable, linear relationship between oxcarbazepine and blood levels is apparent. Furthermore, hepatic enzyme induction ...

journal_title：Journal of affective disorders

authors： Hellewell JS

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Several studies found a high incidence rate of neuro-psychiatric complications during long-term therapy with interferon alpha (IFNalpha), e.g. slowness, severe fatigue, hypersomnia, lethargy, depressed mood, mnemonic troubles, irritability, short temper, emotional lability, social withdrawal, and lack of con...

journal_title：Journal of affective disorders

authors： Bonaccorso S,Marino V,Biondi M,Grimaldi F,Ippoliti F,Maes M

更新日期：2002-12-01 00:00:00